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ATG16L1 Polyclonal Antibody (CAB21763)

SKU:
CAB21763
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€129 - €359
Frequently bought together:

Description

ATG16L1 Polyclonal Antibody (CAB21763)

The ATG16L1 Polyclonal Antibody (CAB21763) is a crucial tool for researchers studying autophagy and its role in various diseases. Autophagy-related protein ATG16L1 is essential for autophagosome formation and plays a key role in maintaining cellular homeostasis. This polyclonal antibody, raised in rabbits, is highly specific to ATG16L1 and is validated for use in various applications such as Western blot and immunofluorescence.ATG16L1 is involved in the autophagy pathway, a highly conserved process in cells that helps remove damaged organelles and proteins, contributing to cellular health and survival. Dysregulation of autophagy has been associated with various diseases, including cancer, neurodegenerative disorders, and inflammatory conditions.

By studying the function of ATG16L1, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify novel therapeutic targets.The ATG16L1 Polyclonal Antibody enables detection and analysis of ATG16L1 protein levels in different cell types and tissues, making it a valuable tool for investigations in the fields of autophagy, cell biology, and disease research. Its high specificity and sensitivity ensure reliable and accurate results, allowing researchers to advance our understanding of autophagy and its implications for human health.

Product Name:ATG16L1 Polyclonal Antibody
Product Code:CAB21763
Reactivity:Human, Mouse, Rat
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human, Mouse, Rat
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:100-1:500
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Positive Samples:Jurkat, Mouse thymus, Rat thymus
Cellular Location:Cytoplasm, Peripheral membrane protein, Preautophagosomal structure membrane

The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 60-300 of human ATG16L1 (NP_110430.5).
Sequence:KHDVP NRHEI SPGHD GTWND NQLQE MAQLR IKHQE ELTEL HKKRG ELAQL VIDLN NQMQR KDREM QMNEA KIAEC LQTIS DLETE CLDLR TKLCD LERAN QTLKD EYDAL QITFT ALEGK LRKTT EENQE LVTRW MAEKA QEANR LNAEN EKDSR RRQAR LQKEL AEAAK EPLPV EQDDD IEVIV DETSD HTEET SPVRA ISRAA TKRLS QPAGG LLDSI TNIFG RRSVS SFPVP QDNVD T
Synonyms:IBD10, WDR30, APG16L, ATG16A, ATG16L
Calculated MW:68kDa
Observed MW:66kDa/68kDa

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