The ATG16L1 Polyclonal Antibody (CAB1871) is a valuable tool for researchers studying ATG16L1, a key player in the autophagy pathway. This antibody, generated in rabbits, has been rigorously tested for its reactivity with human samples and is optimized for use in Western blot applications. By targeting the ATG16L1 protein, this antibody allows for the detection and analysis of autophagy-related processes in various cell types, making it essential for studies in cell biology and disease research.
ATG16L1 is a crucial component of the autophagy machinery, which is responsible for cellular waste removal and maintaining cellular homeostasis. Dysregulation of autophagy has been implicated in various diseases, including cancer, neurodegenerative disorders, and infectious diseases. By investigating the function of ATG16L1, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for intervention.
Product Name:
ATG16L1 Rabbit Polyclonal Antibody
SKU:
CAB1871
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 90-300 of human ATG16L1 (NP_110430.5).
The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
55054
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of A-549 cells using ATG16L1 antibody (CAB1871). Blue: DAPI for nuclear staining.
