The ATG16L1 Polyclonal Antibody (CAB11969) is a vital tool for research involving ATG16L1, a key protein involved in the autophagy pathway. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the ATG16L1 protein, this antibody allows for precise detection and analysis in various cell types, making it an essential component for studies in molecular biology and disease research.ATG16L1 plays a crucial role in the autophagy process, which is essential for maintaining cellular homeostasis and clearing damaged organelles and proteins.
Dysregulation of autophagy has been linked to various diseases, including neurodegenerative disorders, infectious diseases, and cancer. By studying the function of ATG16L1, researchers can gain insights into the mechanisms underlying these diseases and develop potential therapeutic strategies targeting the autophagy pathway.Overall, the ATG16L1 Polyclonal Antibody (CAB11969) provides a valuable tool for scientists conducting research in the fields of molecular biology, cell biology, and disease mechanisms. Its specificity and reliability make it an indispensable resource for understanding the role of ATG16L1 in health and disease.
Product Name:
ATG16L1 Rabbit Polyclonal Antibody
SKU:
CAB11969
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ATG16L1 (NP_110430.5).
The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
55054
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ATG16L1 Rabbit pAb (CAB11969) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
