The ATF5 Polyclonal Antibody (CAB18155) is a valuable tool for researchers studying ATF5, a transcription factor involved in cell survival and proliferation. This rabbit polyclonal antibody is highly specific for ATF5 in human samples and is validated for use in Western blot applications. By binding to the ATF5 protein, this antibody enables researchers to detect and analyze ATF5 expression in a variety of cell types, making it ideal for studies in cell biology, cancer research, and neurobiology.
ATF5 is known for its role in promoting cell growth and survival, making it a potential target for cancer therapy. Its dysregulation has been linked to various cancers and neurodegenerative diseases, highlighting its importance in cellular homeostasis. By studying ATF5 expression and activity, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify novel therapeutic targets.
Product Name:
ATF5 Rabbit Polyclonal Antibody
SKU:
CAB18155
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 101-282 of human ATF5 (NP_036200.2).
Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and tubulin binding activity. Involved in several processes, including fat cell differentiation; regulation of cell cycle process; and regulation of transcription, DNA-templated. Located in centrosome; cytosol; and nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
22809
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from rat lung, using ATF5 Rabbit pAb (CAB18155) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
