ATF4 Rabbit Polyclonal Antibody (CAB0201)
- SKU:
- CAB0201
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | ATF4 Rabbit Polyclonal Antibody |
SKU: | CAB0201 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human ATF4 (NP_001666.2). |
Sequence: | MTEM SFLS SEVL VGDL MSPF DQSG LGAE ESLG LLDD YLEV AKHF KPHG FSSD KAKA GSSE WLAV DGLV SPSN NSKE DAFS GTDW MLEK MDLK EFDL DALL GIDD LETM PDDL LTTL DDTC DLFA PLVQ ETNK QPPQ TVNP IGHL PESL TKPD QVAP FTFL QPLP LSPG VLSS TPDH SFSL ELGS EVDI TEGD RKPD YTAY VAMI PQCI KEED TPSD NDSG ICMS PESY LGSP QHSP STRG SPNR SLPS PGVL CGSA RPKP YDPP GEKM VAAK VKGE KLDK KLKK MEQN KTAA TRYR QKKR AEQE ALTG ECKE LEKK NEAL KERA DSLA KEIQ YLKD LIEE VRKA RGKK RVP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CREB2; TXREB; CREB-2; TAXREB67; ATF4 |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center. |
Calculated MW: | 39kDa |
Observed MW: | 50kDa |
This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication.
Purification Method: | Affinity purification |
Gene ID: | 468 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |