The ATF3 Polyclonal Antibody (CAB13470) is a valuable tool for researchers studying ATF3, a transcription factor that plays a key role in the regulation of stress responses and cell growth control. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.By binding specifically to the ATF3 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it ideal for use in studies focused on molecular biology and cancer research.
ATF3 is known to influence gene expression in response to various stress signals and is implicated in the progression of diseases such as cancer and inflammation.Furthermore, understanding the mechanisms by which ATF3 functions can provide valuable insights into potential therapeutic strategies for targeting ATF3-related pathways in disease treatment. Researchers in the fields of oncology and molecular biology will find the ATF3 Polyclonal Antibody to be a valuable asset in their research endeavors.
Product Name:
ATF3 Rabbit Polyclonal Antibody
SKU:
CAB13470
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-181 of human ATF3 (NP_001665.1).
This gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes.
Purification Method:
Affinity purification
Gene ID:
467
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ATF3 antibody (CAB13470) at 1:1000 dilution. Raw264.7 cells were treated by LPS (1 μg/mL) at 37℃ for 8 hours.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 120s.
