Ataxin-3 (ATXN3) Monoclonal Antibody (CAB22094)
- SKU:
- CAB22094
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | Ataxin-3 (ATXN3) Monoclonal Antibody |
SKU: | CAB22094 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 190-361 of human Ataxin-3 (ATXN3) (NP_004984.2). |
Sequence: | KLIG EELA QLKE QRVH KTDL ERVL EAND GSGM LDED EEDL QRAL ALSR QEID MEDE EADL RRAI QLSM QGSS RNIS QDMT QTSG TNLT SEEL RKRR EAYF EKQQ QKQQ QQQQ QQQQ GDLS GQSS HPCE RPAT SSGA LGSD LGDA MSEE DMLQ AAVT MSLE TVRN DLKT EGKK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | AT3; JOS; MJD; ATX3; MJD1; SCA3; Ataxin-3 (ATXN3) |
Positive Sample: | Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus matrix. |
Calculated MW: | 41kDa |
Observed MW: | 42kDa |
Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Purification Method: | Affinity purification |
Gene ID: | 4287 |
Clone Number: | ARC54882 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |