ATAD3A Rabbit Polyclonal Antibody (CAB8230)
- SKU:
- CAB8230
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | ATAD3A Rabbit Polyclonal Antibody |
SKU: | CAB8230 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human ATAD3A (NP_001164006.1). |
Sequence: | MSWL FGIN KGPK GEGA GPPP PLPP AQPG AEGG GDRG LGDR PAPK DKWS NFDP TGLE RAAK AARE LEHS RYAK DALN LAQM QEQT LQLE QQSK LKEY EAAV EQLK SEQI RAQA EERR KTLS EETR QHQA RAQY QDKL ARQR YEDQ LKQQ QLLN EENL RKQE ESVQ KQEA MRRA TVER EMEL RHKN EMLR VEAE ARAR AKAE RENA DIIR EQIR LKAA EHRQ TVLE SIRT AGTL FGEG FRAF |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:100 - 1:200 |
Synonyms: | HAYOS; PHRINL; ATAD3A |
Positive Sample: | Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion inner membrane, Mitochondrion matrix, Single-pass membrane protein, mitochondrion nucleoid. |
Calculated MW: | 71kDa |
Observed MW: | 68kDa |
This gene encodes a ubiquitously expressed mitochondrial membrane protein that contributes to mitochondrial dynamics, nucleoid organization, protein translation, cell growth, and cholesterol metabolism. This gene is a member of the ATPase family AAA-domain containing 3 gene family which, in humans, includes two other paralogs. Naturally occurring mutations in this gene are associated with distinct neurological syndromes including Harel-Yoon syndrome. High-level expression of this gene is associated with poor survival in breast cancer patients. A homozygous knockout of the orthologous gene in mice results in embryonic lethality at day 7.5 due to growth retardation and defective development of the trophoblast lineage. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 55210 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3. |