ASPSCR1 Rabbit Polyclonal Antibody (CAB7481)
- SKU:
- CAB7481
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ASPSCR1 Rabbit Polyclonal Antibody |
SKU: | CAB7481 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 284-553 of human TUG/ASPSCR1 (NP_076988.1). |
Sequence: | KSKS GQDP QQEQ EQER ERDP QQEQ ERER PVDR EPVD REPV VCHP DLEE RLQA WPAE LPDE FFEL TVDD VRRR LAQL KSER KRLE EAPL VTKA FREA QIKE KLER YPKV ALRV LFPD RYVL QGFF RPSE TVGD LRDF VRSH LGNP ELSF YLFI TPPK TVLD DHTQ TLFQ ANLF PAAL VHLG AEEP AGVY LEPG LLEH AISP SAAD VLVA RYMS RAAG SPSP LPAP DPAP KSEP AAEE GALV PPEP IPGT AQPV KRSL GKVP KWLK LPAS KR |
Tested Applications: | WB IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | TUG; ASPL; ASPS; RCC17; UBXD9; UBXN9; ASPCR1; TUG/ASPSCR1 |
Positive Sample: | 293T,SW480,A-549,BT-474,Mouse liver,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Endomembrane system, Endoplasmic reticulum-Golgi intermediate compartment membrane, Nucleus, Peripheral membrane protein. |
Calculated MW: | 60kDa |
Observed MW: | 80kDa |
The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found.
Purification Method: | Affinity purification |
Gene ID: | 79058 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |