UniProt Protein Function: | ASPRV1: Homodimer (Potential).Protein type: Protease; Membrane protein, integral; EC 3.4.23.-Chromosomal Location of Human Ortholog: 2p13.3Cellular Component: integral to membraneMolecular Function: aspartic-type endopeptidase activityBiological Process: skin development; protein processing; proteolysis |
UniProt Protein Details: | |
NCBI Summary: | Filaggrin is a structural protein that is crucial for in the development and maintenance of the skin barrier. This gene encodes a retroviral-like protease involved in profilaggrin-to-filaggrin processing. Expression is found primarily in the epidermis and inner root sheath of hair follicles. [provided by RefSeq, May 2017] |
UniProt Code: | Q53RT3 |
NCBI GenInfo Identifier: | 189409122 |
NCBI Gene ID: | 151516 |
NCBI Accession: | NP_690005 |
UniProt Secondary Accession: | Q53RT3 |
UniProt Related Accession: | Q53RT3 |
Molecular Weight: | 37kDa |
NCBI Full Name: | retroviral-like aspartic protease 1 |
NCBI Synonym Full Names: | aspartic peptidase retroviral like 1 |
NCBI Official Symbol: | ASPRV1Â Â |
NCBI Official Synonym Symbols: | MUNO; SASP; Taps; SASPase  |
NCBI Protein Information: | retroviral-like aspartic protease 1 |
UniProt Protein Name: | Retroviral-like aspartic protease 1 |
UniProt Synonym Protein Names: | Skin-specific retroviral-like aspartic protease; SASPase; Skin aspartic protease; TPA-inducible aspartic proteinase-like protein; TAPS |
Protein Family: | |
UniProt Gene Name: | ASPRV1Â Â |
UniProt Entry Name: | APRV1_HUMAN |