The ASNS Polyclonal Antibody (CAB16035) is a vital tool for researchers studying the ASNS protein, which plays a crucial role in amino acid metabolism and protein synthesis. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically targeting the ASNS protein, researchers can accurately detect and analyze its expression in various cell types, making it an invaluable tool for studies in biochemistry and molecular biology.ASNS, known as asparagine synthetase, is essential for the biosynthesis of asparagine, a non-essential amino acid with important roles in protein synthesis and cellular functioning.
Dysregulation of ASNS activity has been implicated in various diseases, including cancer, where altered asparagine metabolism can promote tumor growth and progression. By investigating the function of ASNS, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for drug development.
Product Name:
ASNS Rabbit Polyclonal Antibody
SKU:
CAB16035
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 262-561 of human ASNS (NP_001664.3).
The protein encoded by this gene is involved in the synthesis of asparagine. This gene complements a mutation in the temperature-sensitive hamster mutant ts11, which blocks progression through the G1 phase of the cell cycle at nonpermissive temperature. Alternatively spliced transcript variants have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
440
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ASNS Rabbit pAb (CAB16035) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
