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ASNA1 Monoclonal Antibody [PAT2A1AT] (CPAB0603)

SKU:
CPAB0603
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
€149
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Description

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ASNA1 Monoclonal Antibody [PAT2A1AT] (CPAB0603)

The ASNA1 Polyclonal Antibody (CPAB0603) is a valuable tool for researchers studying ASNA1, a gene involved in protein translocation across cellular membranes. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting the ASNA1 protein, this antibody allows for the detection and analysis of ASNA1 in various cell types, making it an ideal choice for investigations in molecular biology and cellular physiology.ASNA1 is essential for the proper targeting and insertion of proteins into the endoplasmic reticulum membrane, playing a crucial role in protein folding and assembly.

Dysregulation of ASNA1 has been linked to various diseases, including neurodegenerative disorders and metabolic conditions, making it a promising target for therapeutic development. By understanding the function of ASNA1, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new treatment strategies.

Product Name:ASNA1 Antibody
Product Sku:CPAB0603
Size:5μg
Host Species:Mouse IgG2b
Immunogen:Anti-human ASNA1 mAb, clone PAT2A1AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ASNA1 protein 1-348 amino acids  purified from Ecoli.
Clone:PAT2A1AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:ASNA1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b
Background:ArsA Arsenite Transporter, ATP-Binding, Homolog 1 (ASNA1) is a part of the arsA ATPase family. ASNA1 is the human homolog of the bacterial arsA gene. ArsA ATPase is the catalytic component of a multisubunit oxyanion pump In E.coli, which is in charge for resistance to arsenicals and antimonials. ASNA1 is also a main component of a transmembrane domain (TMD) recognition complex (TRC) which is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER).
Synonyms:ArsA Arsenite Transporter ATP-Binding Homolog 1 (Bacterial), Arsenical Pump-Driving ATPase, Transmembrane Domain Recognition Complex 40kDa, TRC40. ASNA-I, ATPase ASNA1, ARSA-I, GET3, Golgi To ER Traffic 3 Homolog, Arsenite-Stimulated ATPase, Transmembrane Domain Recognition Complex 40 KDa ATPase Subunit, HASNA-I, HARSA-I, ARSA, ARSA1, EC 3.6.3.16, EC 3.6.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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