ASL Rabbit Polyclonal Antibody (CAB6357)
- SKU:
- CAB6357
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | ASL Rabbit Polyclonal Antibody |
SKU: | CAB6357 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 289-464 of human ASL (NP_000039.2). |
Sequence: | NPDS LELI RSKA GRVF GRCA GLLM TLKG LPST YNKD LQED KEAV FEVS DTMS AVLQ VATG VIST LQIH QENM GQAL SPDM LATD LAYY LVRK GMPF RQAH EASG KAVF MAET KGVA LNQL SLQE LQTI SPLF SGDV ICVW DYGH SVEQ YGAL GGTA RSSV DWQI RQVR ALLQ AQQA |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | ASAL; ASL |
Positive Sample: | HeLa,HepG2,SH-SY5Y,Mouse liver,Mouse brain,Mouse kidney,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, extracellular exosome |
Calculated MW: | 52kDa |
Observed MW: | 49kDa |
This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described.
Purification Method: | Affinity purification |
Gene ID: | 435 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |