ASIP Rabbit Polyclonal Antibody (CAB6872)
- SKU:
- CAB6872
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ASIP Rabbit Polyclonal Antibody |
SKU: | CAB6872 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-132 of human ASIP (NP_001663.2). |
Sequence: | HLPP EEKL RDDR SLRS NSSV NLLD VPSV SIVA LNKK SKQI GRKA AEKK RSSK KEAS MKKV VRPR TPLS APCV ATRN SCKP PAPA CCDP CASC QCRF FRSA CSCR VLSL NC |
Tested Applications: | IHC-P ELISA |
Recommended Dilution: | IHC-P,1:50 - 1:100 |
Synonyms: | ASP; AGSW; AGTI; AGTIL; SHEP9; ASIP |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 15kDa |
In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes.
Purification Method: | Affinity purification |
Gene ID: | 434 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |