ASIC3 Rabbit Polyclonal Antibody (CAB10268)
- SKU:
- CAB10268
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | ASIC3 Rabbit Polyclonal Antibody |
SKU: | CAB10268 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 62-320 of human ASIC3 (NP_064717.1). |
Sequence: | ERVR YYRE FHHQ TALD ERES HRLI FPAV TLCN INPL RRSR LTPN DLHW AGSA LLGL DPAE HAAF LRAL GRPP APPG FMPS PTFD MAQL YARA GHSL DDML LDCR FRGQ PCGP ENFT TIFT RMGK CYTF NSGA DGAE LLTT TRGG MGNG LDIM LDVQ QEEY LPVW RDNE ETPF EVGI RVQI HSQE EPPI IDQL GLGV SPGY QTFV SCQQ QQLS FLPP PWGD CSSA SLNP NYEP EPSD PLGS PSPS PSPP YTLM GCRL ACE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ACCN3; TNaC1; DRASIC; SLNAC1; ASIC3 |
Positive Sample: | Mouse liver,Rat brain,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Multi-pass membrane protein. |
Calculated MW: | 59kDa |
Observed MW: | 59kDa |
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described.
Purification Method: | Affinity purification |
Gene ID: | 9311 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |