ASIC2 Rabbit Polyclonal Antibody (CAB10496)
- SKU:
- CAB10496
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | ASIC2 Rabbit Polyclonal Antibody |
SKU: | CAB10496 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-400 of human ASIC2 (NP_001085.2). |
Sequence: | NLQI PDPH LADP SVLE ALRQ KANF KHYK PKQF SMLE FLHR VGHD LKDM MLYC KFKG QECG HQDF TTVF TKYG KCYM FNSG EDGK PLLT TVKG GTGN GLEI MLDI QQDE YLPI WGET EETT FEAG VKVQ IHSQ SEPP FIQE LGFG VAPG FQTF VATQ EQRL TYLP PPWG ECRS SEMG LDFF PVYS ITAC RIDC ETRY IVEN CNCR MVHM PGDA PFCT PEQH KECA EPAL GLLA EKDS NYCL CRTP CNLT RYNK ELSM VKIP SKTS AKYL EKKF NKSE KYIS E |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 |
Synonyms: | ACCN; BNC1; MDEG; ACCN1; BNaC1; ASIC2a; hBNaC1; ASIC2 |
Positive Sample: | U-251MG,293T,Mouse brain,Rat brain,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Multi-pass membrane protein. |
Calculated MW: | 58kDa |
Observed MW: | 58kDa |
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified.
Purification Method: | Affinity purification |
Gene ID: | 40 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |