ASGR2 Rabbit Polyclonal Antibody (CAB6281)
- SKU:
- CAB6281
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | ASGR2 Rabbit Polyclonal Antibody |
SKU: | CAB6281 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 58-311of human ASGR2 (NP_550435.1). |
Sequence: | CFSL LALS FNIL LLVV ICVT GSQS EGHG GAQL QAEL RSLK EAFS NFSS STLT EVQA ISTH GGSV GDKI TSLG AKLE KQQQ DLKA DHDA LLFH LKHF PVDL RFVA CQME LLHS NGSQ RTCC PVNW VEHQ GSCY WFSH SGKA WAEA EKYC QLEN AHLV VINS WEEQ KFIV QHTN PFNT WIGL TDSD GSWK WVDG TDYR HNYK NWAV TQPD NWHG HELG GSED CVEV QPDG RWND DFCL QVYR WVCE KRRN ATGE VA |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | HL-2; HBXBP; ASGPR2; ASGP-R2; CLEC4H2; ASGR2 |
Positive Sample: | HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type II membrane protein. |
Calculated MW: | 35kDa |
Observed MW: | 41kDa |
This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 433 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |