ASGR1 Rabbit Polyclonal Antibody (CAB13279)
- SKU:
- CAB13279
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | ASGR1 Rabbit Polyclonal Antibody |
SKU: | CAB13279 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 62-291 of human ASGR1 (NP_001662.1). |
Sequence: | QNSQ LQEE LRGL RETF SNFT ASTE AQVK GLST QGGN VGRK MKSL ESQL EKQQ KDLS EDHS SLLL HVKQ FVSD LRSL SCQM AALQ GNGS ERTC CPVN WVEH ERSC YWFS RSGK AWAD ADNY CRLE DAHL VVVT SWEE QKFV QHHI GPVN TWMG LHDQ NGPW KWVD GTDY ETGF KNWR PEQP DDWY GHGL GGGE DCAH FTDD GRWN DDVC QRPY RWVC ETEL DKAS QEPP LL |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | HL-1; ASGPR; ASGPR1; CLEC4H1; ASGR1 |
Positive Sample: | HepG2,22Rv1,SW620,Mouse liver,Mouse lung,Mouse testis,Rat liver,Rat lung,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Secreted, Single-pass type II membrane protein. |
Calculated MW: | 33kDa |
Observed MW: | 45kDa |
This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 432 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |