The ASF1B Polyclonal Antibody (CAB6511) is a valuable tool for researchers studying ASF1B, a histone chaperone involved in chromatin assembly and DNA replication. This antibody, produced in rabbits, is highly specific for detecting ASF1B in human samples and has been validated for Western blot applications. By targeting the ASF1B protein, researchers can investigate its role in various cellular processes, making it essential for studies in molecular biology and cancer research.ASF1B is a critical player in the maintenance of chromatin structure and regulation of gene expression, making it a key target for research into epigenetic mechanisms and cellular proliferation.
Dysregulation of ASF1B has been linked to cancer development and progression, highlighting its potential as a therapeutic target in oncology. Understanding the function of ASF1B is essential for advancing our knowledge of chromatin dynamics and developing targeted therapies for cancer and other diseases.
Product Name:
ASF1B Rabbit Polyclonal Antibody
SKU:
CAB6511
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 63-202 of human ASF1B (NP_060624.1).
This gene encodes a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly.
Purification Method:
Affinity purification
Gene ID:
55723
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ASF1B antibody (CAB6511) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
