The ASCC3 Polyclonal Antibody (CAB7960) is a valuable tool for researchers studying ASCC3, a protein involved in DNA repair and genome stability. This antibody, produced in rabbits, is highly specific to ASCC3 in human samples and is validated for use in Western blot applications. By binding to ASCC3, this antibody allows for the detection and analysis of the protein in various cell types, making it an ideal choice for studies in molecular biology and cancer research.ASCC3, also known as Activating Signal Cointegrator 1 Complex Subunit 3, plays a critical role in maintaining genomic integrity by participating in DNA repair mechanisms.
Dysregulation of ASCC3 has been implicated in various diseases, including cancer, making it a compelling target for research into new therapeutic strategies. Understanding the function of ASCC3 is essential for advancing our knowledge of DNA repair processes and identifying potential targets for drug development in the treatment of cancer and other genetic disorders.
Product Name:
ASCC3 Rabbit Polyclonal Antibody
SKU:
CAB7960
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-111 of human ASCC3 (NP_071374.1).
This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes. The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10973
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using ASCC3 Rabbit pAb (CAB7960) at 1:800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 50s.
