The ASCC2 Polyclonal Antibody (CAB13789) is a valuable tool for researchers studying ASCC2, a protein involved in DNA repair and maintenance of genomic stability. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding to ASCC2 protein, this antibody allows for accurate detection and analysis in various cell types, making it an essential reagent for studies in cancer biology and genomic stability.ASCC2 is known to play a crucial role in the DNA damage response pathway, contributing to the repair of DNA lesions and ensuring the integrity of the genome.
Dysregulation of ASCC2 has been linked to genomic instability and increased susceptibility to cancer development. Therefore, studying the function and regulation of ASCC2 using this polyclonal antibody is essential for gaining insights into the mechanisms underlying DNA repair and genomic stability, with potential implications for cancer therapy and personalized medicine.
Product Name:
ASCC2 Rabbit Polyclonal Antibody
SKU:
CAB13789
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 488-757 of human ASCC2 (NP_115580.2).
Predicted to enable ubiquitin binding activity. Involved in regulation of transcription, DNA-templated; rescue of stalled ribosome; and ribosome-associated ubiquitin-dependent protein catabolic process. Located in nucleus. Part of activating signal cointegrator 1 complex.
Purification Method:
Affinity purification
Gene ID:
84164
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ASCC2 Rabbit pAb (CAB13789) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
