ASCC1 Rabbit Polyclonal Antibody (CAB15832)
- SKU:
- CAB15832
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | ASCC1 Rabbit Polyclonal Antibody |
SKU: | CAB15832 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human ASCC1 (NP_001185727.1). |
Sequence: | MEVL RPQL IRID GRNY RKNP VQEQ TYQH EEDE EDFY QGSM ECAD EPCD AYEV EQTP QGFR STLR APSL LYKH IVGK RGDT RKKI EMET KTSI SIPK PGQD GEIV ITGQ HRNG VISA RTRI DVLL DTFR RKQP FTHF LAFF LNEV EVQE GFLR FQEE VLAK CSMD HGVD SSIF QNPK KLHL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | p50; CGI-18; SMABF2; ASC1p50; ASCC1 |
Positive Sample: | Rat pancreas |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 46kDa |
Observed MW: | 46kDa |
This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 51008 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |