ASC/TMS1 Polyclonal Antibody (CAB22555)
- SKU:
- CAB22555
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | ASC/TMS1 Polyclonal Antibody |
SKU: | CAB22555 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant protein of Mouse ASC/TMS1. |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | Asc; TNS1; masc; CARD5; TMS-1; 9130417A21Rik; ASC/TMS1 |
Positive Sample: | HL-60,THP-1,Jurkat(negative),Mouse spleen,Rat spleen,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | AIM2 inflammasome complex, cytoplasm, cytosol, endoplasmic reticulum, extracellular region, IkappaB kinase complex, inflammasome complex, mitochondrion, NLRP1 inflammasome complex, NLRP3 inflammasome complex, NLRP6 inflammasome complex, nucleolus, nucleoplasm, nucleus |
Calculated MW: | 21kDa |
Observed MW: | 25kDa |
Enables identical protein binding activity and protein dimerization activity. Involved in several processes, including activation of cysteine-type endopeptidase activity; positive regulation of cytokine production; and regulation of defense response. Acts upstream of or within several processes, including defense response to Gram-positive bacterium; positive regulation of macromolecule metabolic process; and regulation of autophagy. Located in cytosol; extracellular region; and nucleus. Part of inflammasome complex. Is expressed in several structures, including alimentary system; brain; heart; hemolymphoid system gland; and urinary system. Orthologous to human PYCARD (PYD and CARD domain containing).
Purification Method: | Affinity purification |
Gene ID: | 66824 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |