The ASC/TMS1 Polyclonal Antibody is a vital tool for researchers studying ASC/TMS1, a key protein involved in inflammasome activation and immune regulation. This antibody, raised in rabbits, is highly specific for human samples and is validated for use in Western blot applications. It binds to ASC/TMS1 with high affinity, enabling precise detection and analysis in a variety of cell types, making it ideal for studies in immunology and inflammatory diseases.ASC/TMS1, also known as PYCARD, is a critical component of the inflammasome complex, which plays a central role in the inflammatory response to infection and tissue damage. Dysregulation of ASC/TMS1 has been associated with a range of inflammatory conditions, making it a promising target for therapeutic intervention.
Research focused on understanding the function of ASC/TMS1 is essential for the development of novel treatments for inflammatory diseases such as autoimmune disorders and inflammatory syndromes.In summary, the ASC/TMS1 Polyclonal Antibody is a valuable tool for researchers investigating the role of ASC/TMS1 in inflammation and immune regulation. Its high specificity and sensitivity make it a reliable option for Western blot analysis, offering insights into the molecular mechanisms underlying inflammatory diseases and potential targets for therapeutic intervention.
Enables identical protein binding activity and protein dimerization activity. Involved in several processes, including activation of cysteine-type endopeptidase activity; positive regulation of cytokine production; and regulation of defense response. Acts upstream of or within several processes, including defense response to Gram-positive bacterium; positive regulation of macromolecule metabolic process; and regulation of autophagy. Located in cytosol; extracellular region; and nucleus. Part of inflammasome complex. Is expressed in several structures, including alimentary system; brain; heart; hemolymphoid system gland; and urinary system. Orthologous to human PYCARD (PYD and CARD domain containing).
Purification Method:
Affinity purification
Gene ID:
66824
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using ASC/TMS1 antibody (CAB22555) at 1:600 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
