ASB9 Antibody (PACO39814)
- SKU:
- PACO39814
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
ASB9 Antibody (PACO39814)
The ASB9 Polyclonal Antibody (PACO39814) is a valuable tool for researchers studying ASB9, a protein involved in cellular pathways regulating protein degradation. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in various applications, including Western blotting.ASB9 is a member of the Ankyrin repeat and SOCS box-containing (ASB) protein family, which play important roles in protein turnover and signaling pathways. ASB9 has been implicated in the regulation of specific target proteins, making it a key player in cellular homeostasis and disease processes.
Understanding the function of ASB9 and its interactions can provide insights into mechanisms underlying various diseases, including cancer and neurodegenerative disorders.By targeting ASB9 with this polyclonal antibody, researchers can detect and analyze ASB9 expression levels in different cell types and tissues, allowing for a better understanding of its role in cellular processes. This antibody is a valuable tool for investigative studies in molecular biology, cell biology, and disease research.
| Antibody Name: | ASB9 Antibody (PACO39814) |
| Antibody SKU: | PACO39814 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Ankyrin repeat and SOCS box protein 9 protein (1-294AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A. |
| Synonyms: | Ankyrin repeat and SOCS box protein 9 (ASB-9), ASB9 |
| UniProt Protein Function: | ASB9: Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Ubiquitin conjugating system Chromosomal Location of Human Ortholog: Xp22.2 Molecular Function:protein binding Biological Process: positive regulation of protein catabolic process; protein ubiquitination |
| NCBI Summary: | This gene encodes a member of the ankyrin repeat and suppressor of cytokine signaling (SOCS) box protein family. Members of this family can interact with the elongin B-C adapter complex via their SOCS box domain and further complex with the cullin and ring box proteins to form E3 ubiquitin ligase complexes. They may function to mediate the substrate-recognition of the E3 ubiquitin ligases. A transcribed pseudogene of this gene has been identified on chromosome 15. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009] |
| UniProt Code: | Q96DX5 |
| NCBI GenInfo Identifier: | 29839756 |
| NCBI Gene ID: | 140462 |
| NCBI Accession: | Q96DX5.1 |
| UniProt Secondary Accession: | Q96DX5,Q9BVF5, Q9NWS5, Q9Y4T3, A8K8A5, |
| UniProt Related Accession: | Q96DX5 |
| Molecular Weight: | 26,849 Da |
| NCBI Full Name: | Ankyrin repeat and SOCS box protein 9 |
| NCBI Synonym Full Names: | ankyrin repeat and SOCS box containing 9 |
| NCBI Official Symbol: | ASB9Â Â |
| NCBI Protein Information: | ankyrin repeat and SOCS box protein 9 |
| UniProt Protein Name: | Ankyrin repeat and SOCS box protein 9 |
| Protein Family: | Ankyrin repeat and SOCS box protein |
| UniProt Gene Name: | ASB9Â Â |
| UniProt Entry Name: | ASB9_HUMAN |
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