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ASB9 Antibody (PACO07876)

SKU:
PACO07876
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459
Frequently bought together:

Description

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ASB9 Antibody (PACO07876)

The ASB9 Polyclonal Antibody (PACO07876) is a valuable tool for researchers studying ASB9, a protein involved in the regulation of immune responses and protein degradation pathways. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications.ASB9 is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins, which play important roles in protein ubiquitination and degradation. ASB9 has been implicated in the regulation of immune signaling pathways and inflammatory responses, making it a potential target for therapeutic interventions in diseases such as cancer and autoimmune disorders.

By specifically binding to ASB9, this antibody allows for the detection and analysis of ASB9 protein levels in various cell types, providing valuable insights into its function and potential therapeutic implications. Researchers in immunology, cancer biology, and protein degradation pathways will find the ASB9 Polyclonal Antibody to be a valuable asset in their studies.

Antibody Name:ASB9 Antibody (PACO07876)
Antibody SKU:PACO07876
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:
Species Reactivity:Human, Mouse
Immunogen:Human ASB9
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity Purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:ankyrin repeat and SOCS box-containing 9;ASB9;DKFZp564L0862;FLJ20636;MGC4954 ;
UniProt Protein Function:ASB9: Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: Xp22.2

Molecular Function:protein binding

Biological Process: positive regulation of protein catabolic process; protein ubiquitination

NCBI Summary:This gene encodes a member of the ankyrin repeat and suppressor of cytokine signaling (SOCS) box protein family. Members of this family can interact with the elongin B-C adapter complex via their SOCS box domain and further complex with the cullin and ring box proteins to form E3 ubiquitin ligase complexes. They may function to mediate the substrate-recognition of the E3 ubiquitin ligases. A transcribed pseudogene of this gene has been identified on chromosome 15. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
UniProt Code:Q96DX5
NCBI GenInfo Identifier:29839756
NCBI Gene ID:140462
NCBI Accession:Q96DX5.1
UniProt Secondary Accession:Q96DX5,Q9BVF5, Q9NWS5, Q9Y4T3, A8K8A5,
UniProt Related Accession:Q96DX5
Molecular Weight:26,849 Da
NCBI Full Name:Ankyrin repeat and SOCS box protein 9
NCBI Synonym Full Names:ankyrin repeat and SOCS box containing 9
NCBI Official Symbol:ASB9  
NCBI Protein Information:ankyrin repeat and SOCS box protein 9
UniProt Protein Name:Ankyrin repeat and SOCS box protein 9
Protein Family:Ankyrin repeat and SOCS box protein
UniProt Gene Name:ASB9  
UniProt Entry Name:ASB9_HUMAN

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