The ASB8 Polyclonal Antibody (PACO07875) is a valuable tool for researchers studying ASB8, a protein involved in the regulation of immune responses. This antibody, developed using rabbit immunization, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the ASB8 protein, the antibody enables the accurate detection and analysis of ASB8 in various cell types, making it an ideal choice for studies in immunology and cancer research.ASB8, also known as Ankyrin repeat and SOCS box protein 8, plays a key role in immune regulation by influencing inflammatory responses and immune cell function.
Its involvement in immune system modulation makes it a promising target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of ASB8 is essential for the development of therapeutic strategies that can exploit or regulate immune responses in these disease contexts.
ankyrin repeat and SOCS box-containing 8;ASB8;FLJ21255;MGC5540;PP14212 ;
UniProt Protein Function:
ASB8: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.Chromosomal Location of Human Ortholog: 12q13.11Cellular Component: cytoplasmBiological Process: protein ubiquitination
