UniProt Protein Function: | Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
UniProt Protein Details: | |
NCBI Summary: | The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contain a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box, similar to the F-box, acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jan 2011] |
UniProt Code: | Q9NWX5 |
NCBI GenInfo Identifier: | 320202962 |
NCBI Gene ID: | 140459 |
NCBI Accession: | NP_001189332.1 |
UniProt Secondary Accession: | Q9NWX5,Q5SZB7, Q9BV15 |
UniProt Related Accession: | Q9NWX5 |
Molecular Weight: | 47 kDa |
NCBI Full Name: | ankyrin repeat and SOCS box protein 6 isoform 3 |
NCBI Synonym Full Names: | ankyrin repeat and SOCS box containing 6 |
NCBI Official Symbol: | ASB6Â Â |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | ankyrin repeat and SOCS box protein 6 |
UniProt Protein Name: | Ankyrin repeat and SOCS box protein 6 |
UniProt Synonym Protein Names: | |
Protein Family: | Ankyrin repeat and SOCS box protein |
UniProt Gene Name: | ASB6Â Â |
UniProt Entry Name: | |