ASB2 Rabbit Polyclonal Antibody (CAB17923)
- SKU:
- CAB17923
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ASB2 Rabbit Polyclonal Antibody |
SKU: | CAB17923 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 448-587 of human ASB2 (NP_057234.2). |
Sequence: | MDLG CDGE PCFS CLYG NGPH PPAP QPSS RFND APAA DKEP SVVQ FCEF VSAP EVSR WAGP IIDV LLDY VGNV QLCS RLKE HIDS FEDW AVIK EKAE PPRP LAHL CRLR VRKA IGKY RIKL LDTL PLPG RLIR YLKY ENTQ |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ASB-2; ASB2 |
Positive Sample: | 293T,rat spleen,rat kidney |
Cellular Localization: | cytoskeleton, cytosol, Z disc |
Calculated MW: | 70kDa |
Observed MW: | 65kDa |
This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 51676 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |