The ASB13 Polyclonal Antibody (CAB15897) is a valuable tool for researchers studying ASB13, a protein involved in various cellular processes such as protein degradation and signal transduction. The antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. It binds specifically to the ASB13 protein, allowing for precise detection and analysis in a variety of cell types, making it an ideal choice for studies in cell biology and signal transduction pathways.
ASB13, also known as Ankyrin repeat and SOCS box protein 13, plays a crucial role in regulating protein turnover and modulating signaling cascades in the cell. Its involvement in these processes highlights its potential significance in diseases such as cancer, neurological disorders, and metabolic conditions. Research into the function of ASB13 is essential for uncovering its role in these diseases and may lead to the development of targeted therapies aimed at modulating its activity for therapeutic benefit.
Product Name:
ASB13 Rabbit Polyclonal Antibody
SKU:
CAB15897
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-278 of human ASB13 (NP_078977.2).
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants, both protein-coding and not protein-coding, have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
79754
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using ASB13 antibody (CAB15897) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
