| UniProt Protein Function: | ASB11: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: Xp22.31 |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011] |
| UniProt Code: | Q8WXH4 |
| NCBI GenInfo Identifier: | 20531990 |
| NCBI Gene ID: | 140456 |
| NCBI Accession: | Q8WXH4.1 |
| UniProt Secondary Accession: | Q8WXH4,Q3SYC4, Q7Z667, E9PEN1 |
| UniProt Related Accession: | Q8WXH4 |
| Molecular Weight: | 32,952 Da |
| NCBI Full Name: | Ankyrin repeat and SOCS box protein 11 |
| NCBI Synonym Full Names: | ankyrin repeat and SOCS box containing 11 |
| NCBI Official Symbol: | ASB11Â Â |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | ankyrin repeat and SOCS box protein 11 |
| UniProt Protein Name: | Ankyrin repeat and SOCS box protein 11 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Ankyrin repeat and SOCS box protein |
| UniProt Gene Name: | ASB11Â Â |
| UniProt Entry Name: | ASB11_HUMAN |
