ASAH2 Rabbit Polyclonal Antibody (CAB12596)
- SKU:
- CAB12596
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | ASAH2 Rabbit Polyclonal Antibody |
SKU: | CAB12596 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-340 of human ASAH2 (NP_001137446.1). |
Sequence: | TATQ TSPV PLTP ESPL FQNF SGYH IGVG RADC TGQV ADIN LMGY GKSG QNAQ GILT RLYS RAFI MAEP DGSN RTVF VSID IGMV SQRL RLEV LNRL QSKY GSLY RRDN VILS GTHT HSGP AGYF QYTV FVIA SEGF SNQT FQHM VTGI LKSI DIAH TNMK PGKI FINK GNVD GVQI NRSP YSYL QNPQ SERA RYSS NTDK EMIV LKMV DLNG DDLG LISW FAIH PVSM NNSN HLVN SDNV GYAS YLLE QEKN KGYL PGQG P |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | HNAC1; BCDase; LCDase; NCDase; N-CDase; ASAH2 |
Positive Sample: | 22Rv1,Mouse kidney,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Single-pass type II membrane protein. |
Calculated MW: | 86kDa |
Observed MW: | 85kDa |
Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).
Purification Method: | Affinity purification |
Gene ID: | 56624 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |