The AS3MT Polyclonal Antibody (CAB16138) is a valuable tool for researchers investigating the AS3MT protein, which plays a key role in arsenic metabolism. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in various applications including Western blotting. By binding specifically to the AS3MT protein, this antibody enables the detection and analysis of AS3MT in different cell types, making it an essential component for studies in environmental toxicology and arsenic-related research.AS3MT, also known as arsenic (+3 oxidation state) methyltransferase, is crucial for the methylation of inorganic arsenic, a process that is essential for the detoxification and elimination of arsenic from the body.
Dysregulation of AS3MT has been linked to arsenic-related diseases such as arsenic-induced skin lesions and cancer. Research into the function and regulation of AS3MT is important for understanding the mechanisms of arsenic toxicity and developing strategies for arsenic exposure mitigation. The AS3MT Polyclonal Antibody is a highly specific and reliable tool for investigating these important processes.
Product Name:
AS3MT Rabbit Polyclonal Antibody
SKU:
CAB16138
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 216-375 of human AS3MT (NP_065733.2).
AS3MT catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to trivalent arsenical and may play a role in arsenic metabolism (Lin et al., 2002 [PubMed 11790780]).
Purification Method:
Affinity purification
Gene ID:
57412
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse spleen, using AS3MT Rabbit pAb (CAB16138) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
