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ART3 Antibody (PACO07871)

SKU:
PACO07871
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459
Frequently bought together:

Description

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ART3 Antibody (PACO07871)

The ART3 Polyclonal Antibody (PACO07871) is a highly specific research tool designed for studying the ART3 protein, an ADP-ribosyltransferase enzyme involved in post-translational modifications. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in various applications such as Western blotting.ART3 plays a crucial role in the ADP-ribosylation process, which regulates various cellular functions including DNA repair, cell signaling, and gene expression. By targeting the ART3 protein, researchers can investigate its functions in different cell types and gain insights into its involvement in physiological processes and disease development.

With its ability to detect and analyze ART3, this antibody is ideal for studies in molecular biology, biochemistry, and pharmacology. By understanding the mechanisms of ART3 action, scientists can potentially develop targeted therapies for diseases related to ADP-ribosylation dysregulation, offering new possibilities for treatment strategies in cancer, neurodegenerative disorders, and other conditions.

Antibody Name:ART3 Antibody (PACO07871)
Antibody SKU:PACO07871
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:
Species Reactivity:Human
Immunogen:Human ART3
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:ADP-ribosyltransferase 3;ART3;FLJ26404 ;
UniProt Protein Function:ART3: an arginine-specific ADP-ribosyltransferase. The encoded protein catalyzes a reversible reaction which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of the modified protein. An ADP-ribosyltransferase pseudogene is located on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
UniProt Protein Details:

Protein type:EC 2.4.2.31; Membrane protein, GPI anchor; Membrane protein, integral; Transferase

Chromosomal Location of Human Ortholog: 4q21.1|4p15.1-p14

Cellular Component: integral to plasma membrane

Molecular Function:NAD+ ADP-ribosyltransferase activity

NCBI Summary:This gene encodes an arginine-specific ADP-ribosyltransferase. The encoded protein catalyzes a reversible reaction which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of the modified protein. An ADP-ribosyltransferase pseudogene is located on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
UniProt Code:Q13508
NCBI GenInfo Identifier:22261808
NCBI Gene ID:419
NCBI Accession:Q13508.2
UniProt Secondary Accession:Q13508,Q53XW3, Q6FHT7, Q8WVJ7, Q93069, Q96HL1,
UniProt Related Accession:Q13508
Molecular Weight:42,716 Da
NCBI Full Name:Ecto-ADP-ribosyltransferase 3
NCBI Synonym Full Names:ADP-ribosyltransferase 3
NCBI Official Symbol:ART3  
NCBI Official Synonym Symbols:ARTC3  
NCBI Protein Information:ecto-ADP-ribosyltransferase 3
UniProt Protein Name:Ecto-ADP-ribosyltransferase 3
UniProt Synonym Protein Names:ADP-ribosyltransferase C2 and C3 toxin-like 3; ARTC3; Mono(ADP-ribosyl)transferase 3; NAD(P)(+)--arginine ADP-ribosyltransferase 3
Protein Family:Ecto-ADP-ribosyltransferase
UniProt Gene Name:ART3  
UniProt Entry Name:NAR3_HUMAN

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