The ARSE Polyclonal Antibody (CAB15644) is a valuable tool for researchers studying ARSE, a protein involved in the activation of the enzyme arylsulfatase E. This antibody, developed using rabbit polyclonal cells, exhibits high reactivity with human samples and has been validated for Western blot applications. By targeting the ARSE protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in biochemistry and enzyme regulation.ARSE plays a crucial role in sulfatase metabolism, particularly in the breakdown of sulfated compounds in the body.
Dysregulation of ARSE activity has been associated with various metabolic disorders and diseases, making it a promising target for therapeutic interventions. By studying ARSE function and regulation, researchers may uncover new insights into disease mechanisms and potential treatment strategies.Overall, the ARSE Polyclonal Antibody (CAB15644) serves as a powerful tool for advancing research in biochemistry, metabolism, and drug discovery. Its specificity and sensitivity in detecting ARSE make it an essential reagent for scientists investigating the role of this enzyme in health and disease.
Product Name:
ARSE Rabbit Polyclonal Antibody
SKU:
CAB15644
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 520-589 of human ARSE (NP_000038.2).
Arylsulfatase E is a member of the sulfatase family. It is glycosylated postranslationally and localized to the golgi apparatus. Sulfatases are essential for the correct composition of bone and cartilage matrix. X-linked chondrodysplasia punctata, a disease characterized by abnormalities in cartilage and bone development, has been linked to mutations in this gene. Alternative splicing results in multiple transcript variants. A pseudogene related to this gene is located on the Y chromosome.
Purification Method:
Affinity purification
Gene ID:
415
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ARSE Rabbit pAb (CAB15644) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
