The ARRDC4 Polyclonal Antibody (CAB18522) is a valuable tool for researchers studying ARRDC4, a protein involved in various cellular processes such as endosomal trafficking and protein degradation. This antibody, generated in rabbits, is highly specific for detecting ARRDC4 in human samples and is validated for use in Western blot applications.ARRDC4 is known to play a role in regulating protein turnover and intracellular signaling pathways, making it a key player in maintaining cellular homeostasis. Studies have shown that dysregulation of ARRDC4 can lead to various diseases, including cancer and neurodegenerative disorders.
Therefore, understanding the function of ARRDC4 is essential for developing targeted treatments for these conditions.With its high reactivity and specificity, the ARRDC4 Polyclonal Antibody (CAB18522) is an excellent tool for researchers looking to investigate the role of ARRDC4 in cellular processes and disease pathogenesis. Whether studying protein degradation mechanisms or exploring novel therapeutic targets, this antibody provides reliable and accurate detection of ARRDC4 in various cell types, making it an indispensable resource for molecular and cellular biology research.
Product Name:
ARRDC4 Rabbit Polyclonal Antibody
SKU:
CAB18522
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human ARRDC4 (NP_899232.2).
cytoplasm, early endosome, endosome, extracellular vesicle, plasma membrane
Calculated MW:
45kDa
Observed MW:
45kDa
Predicted to enable ubiquitin ligase-substrate adaptor activity. Acts upstream of or within positive regulation of ubiquitin-protein transferase activity. Located in endosome and plasma membrane.
Purification Method:
Affinity purification
Gene ID:
91947
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from PC-3 cells, using ARRDC4 pAb (CAB18522) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
