The ARR3 Polyclonal Antibody (CAB13009) is specifically designed for research involving ARR3, a key protein involved in the regulation of immune responses in the body. This antibody, generated in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the ARR3 protein, this antibody allows for the detection and analysis of ARR3 in a variety of cell types, making it an essential tool for studies in immunology and cancer research.ARR3, also known as Arrestin 3, plays a crucial role in immune regulation by modulating signaling pathways involved in inflammation and immune cell activation.
Its involvement in immune response modulation makes it a valuable target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. By studying the activity of ARR3, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially develop novel therapeutic strategies targeting ARR3 for immune modulation.
Product Name:
ARR3 Rabbit Polyclonal Antibody
SKU:
CAB13009
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ARR3 (NP_004303.2).
The protein encoded by this gene is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function.
Purification Method:
Affinity purification
Gene ID:
407
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ARR3 Rabbit pAb (CAB13009) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
