The ARPC2 Polyclonal Antibody (CAB10791) is a valuable tool for researchers studying ARPC2, a key protein involved in cell motility and actin filament assembly. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the ARPC2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it essential for investigations in cell biology, cancer research, and cytoskeletal dynamics.ARPC2, part of the Arp2/3 complex, plays a crucial role in promoting actin polymerization and cell migration, processes that are fundamental for cellular function and development.
Dysregulation of ARPC2 expression or function has been implicated in various diseases, including cancer metastasis and neurological disorders. By investigating the role of ARPC2 using this antibody, researchers can gain insights into the mechanisms of cellular movement and potential therapeutic targets for diseases associated with aberrant cell mobility.
Product Name:
ARPC2 Rabbit Polyclonal Antibody
SKU:
CAB10791
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ARPC2 (NP_690601.1).
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined.
Purification Method:
Affinity purification
Gene ID:
10109
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ARPC2 Rabbit pAb (CAB10791) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
