The AROD Antibody (PACO34338) is a polyclonal antibody developed for research involving AROD, a key protein involved in cholesterol metabolism and lipid homeostasis. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in various applications including Western blotting and immunofluorescence.AROD, also known as Delta-24-dehydrocholesterol reductase, plays a crucial role in the biosynthesis of cholesterol and other sterols, making it a potential target for research in metabolic disorders, cardiovascular diseases, and lipid-related conditions. By binding specifically to the AROD protein, this antibody enables accurate detection and analysis of AROD expression in different cell types, offering valuable insights for studies in lipid metabolism and related pathways.
Furthermore, the AROD Antibody can be instrumental in investigating the impact of AROD dysregulation on cellular processes and its potential implications in disease development. Its high specificity and sensitivity make it a reliable tool for researchers exploring the role of AROD in various biological contexts, ultimately contributing to advancements in understanding cholesterol metabolism and therapeutic strategies targeting lipid-related disorders.
Antibody Name:
aroD Antibody (PACO34338)
Antibody SKU:
PACO34338
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Salmonella typhi
Immunogen:
Recombinant Salmonella typhi 3-dehydroquinate dehydratase protein (1-252AA)
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acid,. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. The reaction involves the formation of an imine intermediate between the keto group of 3-dehydroquinate and the epsylon-amino group of Lys-170 at the active site.
Synonyms:
3-dehydroquinate dehydratase (3-dehydroquinase) (EC 4.2.1.10) (Type I DHQase) (Type I dehydroquinase) (DHQ1), aroD
UniProt Protein Function:
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. The reaction involves the formation of an imine intermediate between the keto group of 3-dehydroquinate and the epsylon-amino group of Lys-170 at the active site.
