ARNT2 Rabbit Polyclonal Antibody (CAB8060)
- SKU:
- CAB8060
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | ARNT2 Rabbit Polyclonal Antibody |
SKU: | CAB8060 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 440-690 of human ARNT2 (NP_055677.3). |
Sequence: | QLQQ QQAE LEVH QRDG LSSY DLSQ VPVP NLPA GVHE AGKS VEKA DAIF SQER DPRF AEMF AGIS ASEK KMMS SASA AGTQ QIYS QGSP FPSG HSGK AFSS SVVH VPGV NDIQ SSSS TGQN MSQI SRQL NQSQ VAWT GSRP PFPG QQIP SQSS KTQS SPFG IGTS HTYP ADPS SYSP LSSP ATSS PSGN AYSS LANR TPGF AESG QSSG QFQG RPSE VWSQ WQSQ HHGQ QSGE QHSH QQPG QTEV FQDM LPM |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | WEDAS; bHLHe1; ARNT2 |
Positive Sample: | Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 79kDa |
Observed MW: | 79-85kDa |
This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.
Purification Method: | Affinity purification |
Gene ID: | 9915 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |