The ARMT1 Polyclonal Antibody (PAC040822) is a valuable tool for researchers investigating ARMT1, a protein involved in various cellular processes, including protein trafficking and lipid metabolism. This antibody, produced in rabbits, boasts high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to ARMT1, this antibody enables precise detection and analysis in a variety of cell types, making it a versatile tool for studies in cell biology and metabolism.
ARMT1 is known for its role in lipid metabolism and protein sorting, making it a key player in maintaining cellular homeostasis. Its involvement in these fundamental processes highlights its importance in various pathological conditions, including metabolic disorders and cancer. By uncovering the functions of ARMT1, researchers can gain crucial insights into disease mechanisms and potentially identify new therapeutic targets for intervention.
Western blot. All lanes: ARMT1 antibody at 0.6µg/ml. Lane 1: MCF-7 whole cell lysate. Lane 2: A431 whole cell lysate. Lane 3: 293T whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 52 kDa. Observed band size: 52 kDa.
Immunohistochemistry of paraffin-embedded human breast cancer using PACO40822 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human testis tissue using PACO40822 at dilution of 1:100.
Background:
O-methyltransferase that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Methylates PCNA, suggesting it is involved in the DNA damage response.
ARMT1: Belongs to the UPF0364 family.Chromosomal Location of Human Ortholog: 6q25.1Molecular Function: enzyme binding; protein binding; S-adenosylmethionine-dependent methyltransferase activityBiological Process: methylation; protein amino acid methylation; response to DNA damage stimulus