The ARMS2 Polyclonal Antibody (CAB10161) is a valuable tool for researchers studying the ARMS2 gene, which has been implicated in the development of age-related macular degeneration (AMD). This antibody, derived from rabbits, is highly specific for human samples and has been validated for use in Western blotting applications.ARMS2, also known as age-related maculopathy susceptibility 2, is a protein involved in mitochondrial function and oxidative stress response in the retina. Mutations in the ARMS2 gene have been associated with an increased risk of developing AMD, a leading cause of vision loss in the elderly population.
By using the ARMS2 Polyclonal Antibody, researchers can detect and analyze ARMS2 protein levels in various cell types, shedding light on its role in the pathogenesis of AMD and potentially identifying new therapeutic targets for the disease. This antibody is a valuable tool for studies in ophthalmology, genetics, and aging-related research, helping to advance our understanding of AMD and potentially leading to the development of new treatment options.
Product Name:
ARMS2 Rabbit Polyclonal Antibody
SKU:
CAB10161
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-107 of human ARMS2 (NP_001093137.1).
This gene encodes a small secreted protein specific to primates. This protein is a component of the choroidal extracellular matrix of the eye. Mutations in this gene are associated with age-related macular degeneration.
Purification Method:
Affinity purification
Gene ID:
387715
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse eye, using ARMS2 antibody (CAB10161) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
