ARMET/ARP/MANF Monoclonal Antibody (CAB21080)
- SKU:
- CAB21080
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | ARMET/ARP/MANF Monoclonal Antibody |
SKU: | CAB21080 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-182 of human MANF (NP_006001.5). |
Sequence: | LRPG DCEV CISY LGRF YQDL KDRD VTFS PATI ENEL IKFC REAR GKEN RLCY YIGA TDDA ATKI INEV SKPL AHHI PVEK ICEK LKKK DSQI CELK YDKQ IDLS TVDL KKLR VKEL KKIL DDWG ETCK GCAE KSDY IRKI NELM PKYA PKAA SART DL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | ARP; ARMET; ARMET/ARP/MANF |
Positive Sample: | HT-29,HepG2,BxPC-3,Mouse pancreas,Mouse testis,Mouse heart,Rat pancreas,Rat liver,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 21kDa |
Observed MW: | 16kDa |
The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related.
Purification Method: | Affinity purification |
Gene ID: | 7873 |
Clone Number: | ARC52199 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |