The ARMCX1 Antibody (PACO15528) is a valuable tool for researchers studying the ARMCX1 protein, which plays a key role in cellular processes such as mitochondrial dynamics and apoptosis. This polyclonal antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.ARMCX1, also known as Armadillo repeat containing X-linked protein 1, is involved in regulating mitochondrial morphology and function, making it a potential target for studies in mitochondrial biology and cell death pathways. By binding to the ARMCX1 protein, this antibody allows for the detection and analysis of ARMCX1 in various cell types, providing researchers with important insights into its function and potential therapeutic applications.
Research involving ARMCX1 is particularly relevant in the fields of cancer biology, neurodegenerative diseases, and mitochondrial disorders, where dysregulation of mitochondrial dynamics and cell death pathways can contribute to disease progression. By understanding the role of ARMCX1 in these processes, researchers can uncover new strategies for developing targeted therapies and interventions to treat these conditions effectively.
Antibody Name:
ARMCX1 Antibody (PACO15528)
Antibody SKU:
PACO15528
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Fusion protein of human ARMCX1
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15528(ARMCX1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15528(ARMCX1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
Background:
This gene encodes a member of the ALEX family of proteins and may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and two Armadillo (arm) repeats. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members, including ALEX2 and ALEX3, on the X chromosome.
Synonyms:
armadillo repeat containing, X-linked 1
UniProt Protein Function:
ARMCX1: Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: Xq22.1Cellular Component: integral to membrane
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the ALEX family of proteins and may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and two Armadillo (arm) repeats. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members, including ALEX2 and ALEX3, on the X chromosome. [provided by RefSeq, Jul 2008]
armadillo repeat-containing X-linked protein 1; ARM protein lost in epithelial cancers on chromosome X 1; arm protein lost in epithelial cancers, X chromosome, 1
UniProt Protein Name:
Armadillo repeat-containing X-linked protein 1
UniProt Synonym Protein Names:
ARM protein lost in epithelial cancers on chromosome X 1; Protein ALEX1
