The ARMC8 Polyclonal Antibody (PACO07856) is a crucial tool for researchers studying the ARMC8 protein, a component of the intraflagellar transport complex involved in ciliary assembly and maintenance. This antibody, produced in rabbits, exhibits strong reactivity with human samples and is validated for use in Western blotting applications. By binding specifically to ARMC8, researchers can detect and analyze this protein in a variety of cell types, making it ideal for investigations in cell biology and ciliopathy research.
ARMC8 is essential for the proper formation and function of cilia, hair-like structures found on the surface of many cell types that play key roles in cell signaling and sensory functions. Dysregulation of ciliary proteins such as ARMC8 has been linked to various genetic disorders and diseases, making them important targets for therapeutic intervention. Understanding the function of ARMC8 is crucial for advancing our knowledge of ciliopathies and developing treatments for related conditions.
ARMC8: 4 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 3q22.3