The ARL8A Polyclonal Antibody (PAC007852) is a valuable tool for researchers studying the ARL8A protein, which plays a vital role in regulating intracellular transport and membrane dynamics. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot assays. By targeting the ARL8A protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal choice for studies in cell biology and organelle dynamics.ARL8A is a small GTPase that is involved in the regulation of lysosome positioning and trafficking, as well as autophagy and endocytic pathways.
Its functions in these processes make it a key target for research related to cellular homeostasis, membrane trafficking, and organelle function. Understanding the role of ARL8A can provide valuable insights into various cellular processes and may offer potential therapeutic opportunities for diseases associated with dysregulated organelle dynamics and trafficking.
ARL8A: May play a role in lysosomes motility. Alternatively, may play a role in chromosome segregation. Belongs to the small GTPase superfamily. Arf family.Protein type: G protein, monomeric; G protein, monomeric, ARFChromosomal Location of Human Ortholog: 1q32.1Cellular Component: cytoplasm; lysosomal membrane; membrane; midbody; spindle midzoneMolecular Function: alpha-tubulin binding; beta-tubulin binding; GTP binding; protein bindingBiological Process: chromosome segregation