The ARL6IP5 Polyclonal Antibody (CAB14842) is a valuable tool for researchers studying ARL6IP5, a protein involved in intracellular trafficking and ciliary function. This antibody, produced in rabbits, exhibits high specificity for human samples and is suitable for use in Western blot applications. By binding to the ARL6IP5 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an ideal choice for research in cell biology and signal transduction pathways.ARL6IP5, also known as BART, is essential for maintaining proper cellular organization and function.
Its role in vesicle trafficking and ciliary transport highlights its importance in various cellular processes. Research on ARL6IP5 is particularly relevant in the study of ciliopathies, genetic disorders that affect cilia structure and function. Understanding the function of ARL6IP5 can provide valuable insights into these conditions and potentially lead to the development of therapies targeting ciliary dysfunction.
Product Name:
ARL6IP5 Rabbit Polyclonal Antibody
SKU:
CAB14842
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human ARL6IP5 (NP_006398.1).
Expression of this gene is affected by vitamin A. The encoded protein of this gene may be associated with the cytoskeleton. A similar protein in rats may play a role in the regulation of cell differentiation. The rat protein binds and inhibits the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport.
Purification Method:
Affinity purification
Gene ID:
10550
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse thymus, using ARL6IP5 Rabbit pAb (CAB14842) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
