The ARL6IP1 Polyclonal Antibody (CAB17107) is a valuable tool for researchers studying ARL6IP1, a protein involved in cellular processes like intracellular trafficking and ciliogenesis. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the ARL6IP1 protein, this antibody enables the detection and analysis of ARL6IP1 in various cell types, making it ideal for research in cell biology and molecular biology.ARL6IP1 is known to play important roles in regulating protein trafficking within cells and maintaining the structure and function of cilia, which are hair-like structures on the cell surface involved in cell signaling and movement.
Dysregulation of ARL6IP1 function has been associated with various diseases, including ciliopathy disorders and cancer. Therefore, studying the function of ARL6IP1 is essential for gaining insights into these pathological conditions and developing targeted therapies.Overall, the ARL6IP1 Polyclonal Antibody (CAB17107) offers researchers a reliable tool for investigating the functions and mechanisms of ARL6IP1 in cellular processes and disease pathogenesis. Its specificity and sensitivity make it a valuable asset for studies in cell biology, molecular biology, and related fields.
Product Name:
ARL6IP1 Rabbit Polyclonal Antibody
SKU:
CAB17107
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ARL6IP1 (NP_055976.1).
This gene belongs to the ARL6ip family and encodes a transmembrane protein that is predominantly localized to intracytoplasmic membranes. It is highly expressed in early myeloid progenitor cells and thought to be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Mutations in this gene are associated with spastic paraplegia 61 (SPG61). Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
23204
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using ARL6IP1 Rabbit pAb (CAB17107) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
