The ARL6 Polyclonal Antibody (CAB8269) is a valuable tool for researchers studying ARL6, a protein associated with intracellular trafficking and ciliary function. This antibody, raised in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the ARL6 protein, this antibody allows for the detection and analysis of ARL6 in various cell types, making it ideal for research in cell biology and ciliary biology.ARL6 is known to play a crucial role in vesicular trafficking and ciliary function, making it a key player in cellular processes such as protein transport and signaling.
Dysfunction of ARL6 has been implicated in various diseases, including ciliopathies and cancer, highlighting the importance of studying this protein in research. By understanding the function and regulation of ARL6, researchers can gain insight into its role in disease pathogenesis and potentially develop targeted therapies.
Product Name:
ARL6 Rabbit Polyclonal Antibody
SKU:
CAB8269
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-186 of human ARL6 (NP_115522.1).
The protein encoded by this gene belongs to the ARF-like (ADP ribosylation factor-like) sub-family of the ARF family of GTP-binding proteins which are involved in regulation of intracellular traffic. Mutations in this gene are associated with Bardet-Biedl syndrome (BBS). A vision-specific transcript, encoding long isoform BBS3L, has been described (PMID: 20333246).
Purification Method:
Affinity purification
Gene ID:
84100
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using ARL6 Rabbit pAb (CAB8269) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
