The ARL6 Polyclonal Antibody (CAB15198) is a valuable tool for researchers studying ARL6, a protein involved in intracellular vesicle trafficking and cellular transport processes. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the ARL6 protein, this antibody allows for the detection and analysis of ARL6 expression in various cell types, making it suitable for investigations in cell biology and molecular biology.ARL6 is essential for maintaining proper cellular function and organelle dynamics, with dysregulation of ARL6 implicated in various diseases including neurodegenerative disorders and metabolic conditions.
Its role in intracellular trafficking pathways and membrane organization highlights its importance in cellular physiology and presents opportunities for targeted therapeutic interventions. Research utilizing the ARL6 Polyclonal Antibody is vital for advancing our understanding of ARL6 function and its potential implications in disease pathogenesis.
Product Name:
ARL6 Rabbit Polyclonal Antibody
SKU:
CAB15198
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-186 of human ARL6 (NP_115522.1).
The protein encoded by this gene belongs to the ARF-like (ADP ribosylation factor-like) sub-family of the ARF family of GTP-binding proteins which are involved in regulation of intracellular traffic. Mutations in this gene are associated with Bardet-Biedl syndrome (BBS). A vision-specific transcript, encoding long isoform BBS3L, has been described (PMID: 20333246).
Purification Method:
Affinity purification
Gene ID:
84100
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of U2OS cells using ARL6 antibody (CAB15198) at dilution of 1:100. Blue: DAPI for nuclear staining.
